There are small group of enzymes which are specifically suited to the detoxification and removal of 4-HNE from cells. Within this group are the glutathione S-transferases (GSTs) such as hGSTA4-4 and hGST5.8, aldose reductase, and aldehyde dehydrogenase. These enzymes have low Km values for HNE catalysis and together are very efficient at controlling the intracellular [...]
Detoxification
The latest articles related to Detoxification
*Mental health services. Individualized treatment designed to assist patients in reaching and maintaining psychiatric stability and in developing the necessary skills and supports to succeed in community settings. Services are provided in the inpatient psychiatric facility and in two community-based apartment buildings. *Chemical health services. Inpatient and outpatient services, including mental illness/chemical dependency services. *Sub-acute [...]
Introduction A brief introduction (by Goldacre) touching on subjects covered by subsequent chapters. It bemoans the widespread lack of understanding of evidence-based science. Chapter 1: Matter Detoxification methods (the Aqua Detox, ear candles etc.) that can easily be shown to be bogus by simple experiments. Discusses the “detox phenomenon.” Touches on purification rituals. Chapter 2: [...]

The first-born child of Edith and Arthur Gittleman, Gittleman grew up in West Hartford, Connecticut, attending Conard High School (1964–1967) where she graduated with high honors. Active as a Parade of Youth correspondent for the ”Hartford Courant” (coming in 2nd place for the state) and president of the Service Club, she also attended religious school [...]

Lofexidine is not an opioid, whereas methadone is. Some opioid detox programs use methadone in decreasing amounts in their detox protocol, whereas other detox programs use lofexidine. The drugs are completely chemically unrelated, and their physiological effects are completely unrelated, although both are used as part of an opioid detoxification protocol. Whereas lofexidine cannot stop [...]

Some food toxins can be reduced by pressure cooking. A Korean study of aflatoxins in rice (associated with ”Aspergillus” fungus) showed that pressure cooking was capable of reducing aflatoxin concentrations to between 12 and 22% of the amount in the uncooked rice. Adapted from the Wikipedia article Pressure cooking, under the G. N. U. Free [...]

The principal physiological function of glyoxalase I is the detoxification of methylglyoxal, a reactive 2-oxoaldehyde that is cytostatic at low concentrations and cytotoxic at millimolar concentrations. Methylglyoxal is a by-product of normal biochemistry that is a carcinogen, a mutagen and can chemically damage several components of the cell, such as proteins and nucleic acids. Methylglyoxal [...]


